The 22-year-old was forced off in the first half of the defeat, and specialists this week have confirmed that the injury requires surgery.
As well as the following update on Neto, the medical team also provided an update on Hee Chan Hwang and Bruno Jordao, after recent injuries...
"Pedro sustained an ankle injury against West Ham on Saturday where he strained the lateral ligaments.
"Following further evaluation and a specialist opinion this week, it is planned for him to undergo surgery. This means that, unfortunately, he will not be fit for the upcoming World Cup.
"Hee Chan has made good progress this week and has rejoined team training.
"Bruno Jordao injured his groin while on loan at CD Santa Clara in September and was unable to play with confidence after rehabilitation. He has therefore returned to the UK to undergo groin surgery. He is expected to return to play in the New Year."
